Downtown Clayton Vacation Packages

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Top Holiday Package Deals in Downtown Clayton

Price found within the past 48 hours. Click for updated prices.
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
Midtown
Price was CA $1,628, price is now CA $1,366 per person
CA $1,366
per person
Dec 16 - Dec 23
found 16 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
7.8/10 Good! (1,001 reviews)

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $2,200, price is now CA $1,395 per person
CA $1,395
per person
Dec 16 - Dec 23
found 16 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (1,677 reviews)

The Cheshire

The Cheshire

4 out of 5
Price was CA $2,103, price is now CA $1,692 per person
CA $1,692
per person
Dec 16 - Dec 23
found 16 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (1,010 reviews)
A wonderful break from boring hotels! My kids loved all the artwork and the scavenger hunt. The pub food and drinks were fantastic, as was the hotel breakfast each morning. We will definitely plan to return.

Reviewed on Nov 9, 2026

Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Price was CA $2,091, price is now CA $1,735 per person
CA $1,735
per person
Dec 16 - Dec 23
found 16 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9/10 Wonderful! (2,047 reviews)

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was CA $2,151, price is now CA $1,809 per person
CA $1,809
per person
Dec 16 - Dec 23
found 16 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.6/10 Excellent! (1,080 reviews)
We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of hotel.

Reviewed on Nov 8, 2026

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Clayton
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

4 out of top 10 points of interest in this area

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotels in Downtown St. Louis

Downtown Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $148 per night from Dec 6 to Dec 7
CA $148
CA $172 total
Dec 6 - Dec 7
includes taxes & fees
8.8/10 Excellent! (3,530 reviews)
"The staff were very kind and welcoming! We enjoyed our stay. The rooms were very clean and comfortable. It also has a lovely breakfast. My favorite part about my stay was definitely the entire staff though I can’t say enough how wonderful everyone was."

Reviewed on Nov 9, 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $215 per night from Nov 22 to Nov 23
CA $215
CA $253 total
Nov 22 - Nov 23
includes taxes & fees
Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

2 out of 5
227 South Central Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $181 per night from Nov 15 to Nov 16
CA $181
CA $212 total
Nov 15 - Nov 16
includes taxes & fees
9.2/10 Wonderful! (426 reviews)
"Nice place very clean, shower pressure was kind of weak"

Reviewed on Nov 7, 2026

AC Hotel St. Louis Clayton
See all 1,960 properties in Downtown Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
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Frequently asked questions

How much does a Downtown Clayton vacation package cost?
Less than you might think — from just CA $1,366, as a matter of fact! By combining hotels, flights and car rentals into a custom-made travel package, your Downtown Clayton escape is just a few clicks away.
How do I get a cheap travel package to Downtown Clayton?
Imagine all the wonderful things you could do in Downtown Clayton with a pile of extra cash in your wallet. Watch your savings stack up when you combine your travel bookings into a Downtown Clayton vacation package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 air carriers and 1,000,000 properties throughout the world. Whether you're taking off with the whole family or surprising your special someone, organizing a trip to Downtown Clayton is better with a package.
Where should I stay in Downtown Clayton?
Most people who visit Downtown Clayton include both St. Louis Zoo and Cathedral Basilica of St. Louis on their bucket lists. Why not go for a hotel that's close to these iconic attractions?
What are the top hotels in Downtown Clayton?
King Bed, Comfy Environment, Cozy Space and Le Méridien St. Louis Clayton are among the most well-known properties in Downtown Clayton. Why not look up the amenities and facilities at each and then decide?
How far in advance should I book my Downtown Clayton vacation?
Your safest bet is to book early. Air carriers generally advertise flights around a year in advance, and this is a fantastic opportunity to land some rock-bottom prices. Just been told you should take all your vacation days next month? That's alright! Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Downtown Clayton travel package include?
That depends on what sort of escape you're planning. Downtown Clayton vacation deals can include car rentals, hotels and flights. You can mix and match to create the package that works for you! You can also add on activities and experiences after you've booked to land even bigger discounts.
What should I know before booking a Downtown Clayton travel package?
When you book your flights, hotels and car rentals together, you'll walk away with fantastic discounts. Whether you're organizing a beach break in a villa or prefer to stay in a convenient hotel in the city, Expedia will make it happen for less.
Can I choose my airline with a Downtown Clayton Expedia vacation package?
Expedia offers access to more than 550 airline partners worldwide, so you sure can! Simply choose your preferred air carrier and create the perfect Downtown Clayton trip.
If I'm not able to travel, can I cancel my Downtown Clayton vacation package?
It's hard to predict what the future holds, so it's good to know that you can change or cancel your Downtown Clayton vacation package. If you booked in the last 24 hours, you may be eligible for a refund. If it's an older booking, your airline, hotel or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Things to do

The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

CA $247
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Landmarks Downtown-East Walking Tour

Landmarks Downtown-East Walking Tour

CA $28
per adult
Landmarks Downtown-East Walking Tour
Haunted Lemp Brewery Bottle Works Paranormal Tour

Haunted Lemp Brewery Bottle Works Paranormal Tour

CA $35
per adult
Haunted Lemp Brewery Bottle Works Paranormal Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.